INSPIRATIONS FROM HISTORY |
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Year : 2015 | Volume
: 20
| Issue : 1 | Page : 41-43 |
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Tracing the journey of disulfiram: From an unintended discovery to a treatment option for alcoholism
Arghya Pal, Raman Deep Pattanayak, Rajesh Sagar
Department of Psychiatry, All India Institute of Medical Sciences, New Delhi, India
Correspondence Address:
Raman Deep Pattanayak Department of Psychiatry, All India Institute of Medical Sciences, New Delhi India
 Source of Support: None, Conflict of Interest: None  | Check |
DOI: 10.4103/0971-8990.164826
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Disulfiram is a drug that has been used as a deterrent agent in the treatment of alcohol use disorders. This section ventures into the journey of the discovery of the molecule, starting from the accidental discovery of its potential pathophysiological effects, thereafter becoming obscure due to lack of indications (alcohol use was not considered a problem!); and finally making a comeback and standing the rigorous test of time due to the determination of a few researchers, which makes it a story worth revisiting. |
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